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Article

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease.

Scientific reports - 24 Jan 2017

Sandor Cynthia, Honti Frantisek, Haerty Wilfried, Szewczyk-Krolikowski Konrad, Tomlinson Paul, Evetts Sam, Millin Stephanie, Keane Thomas, McCarthy Shane A, Durbin Richard, Talbot Kevin, Hu Michele, Webber Caleb, Ponting Chris P, Wade-Martins Richard

Abstract excerpt

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, affecting 1% of the population over 65 years characterized clinically by both motor and non-motor symptoms accompanied by the preferential loss of dopamine neurons in the substantia nigra pars compacta. Here, we sequenced the exomes of 244 Parkinson's patients selected from the Oxford Parkinson's Disease Centre Discovery Cohort and,...

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Identifiers

PMID: 28117402
DOI: 10.1038/srep41188
PMCID: PMC5259721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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