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Article

Disruption of dopamine homeostasis has sexually dimorphic effects on senescence characteristics of Drosophila melanogaster.

The European journal of neuroscience - 1 Mar 2017

Bednářová Andrea, Hanna Marley E, Rakshit Kuntol, O'Donnell Janis M, Krishnan Natraj

Abstract excerpt

The neurotransmitter dopamine (DA) is known to be involved in a multitude of physiological processes. We investigated sexually dimorphic effects of disruptions in DA homeostasis and its relationship to senescence using three different Drosophila melanogaster mutants namely Catsup (Catsup26 ) with elevated DA levels, and pale (ple2 ), Punch (PuZ22 ) with depleted DA levels. In all genotypes including controls, DA...

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Identifiers

PMID: 28112452
DOI: 10.1111/ejn.13525
PMCID: PMC5359053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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