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Article

Alteration of methylation status in the ATXN3 gene promoter region is linked to the SCA3/MJD.

Neurobiology of aging - 1 May 2017

Wang Chunrong, Peng Huirong, Li Jiada, Ding Dongxue, Chen Zhao, Long Zhe, Peng Yun, Zhou Xin, Ye Wei, Li Kai, Xu Qian, Ai Sanxi, Song Chengyuan, Weng Ling, Qiu Rong, Xia Kun, Tang Beisha, Jiang Hong

Abstract excerpt

DNA methylation has been acknowledged as one of the key epigenetic mechanisms involved in the regulation of gene expression and genomic functions. Alteration of the DNA methylation level has been linked to modification of the disease progression and instability regulation of certain disease-causing repeats in neurodegenerative diseases. In this study, blood samples collected from spinocerebellar ataxia type...

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Source

Identifiers

PMID: 28094059
DOI: 10.1016/j.neurobiolaging.2016.12.014

Genes

ATXN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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