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Article

A novel embryo culture media supplement that improves pregnancy rates in mice

10 Jan 2017

Abstract excerpt

The preimplantation embryo in vivo is exposed to numerous growth factors in the female reproductive tract, which are not recapitulated in embryo culture media in vitro The IGF2 and plasminogen activator systems facilitate blastocyst development. We hypothesized that the addition of IGF2 in combination with urokinase plasminogen activator (uPA) and plasminogen could improve rates of blastocyst hatching and...

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Share to Prenatal Screening and Diagnostics
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PMID: 28073983
DOI: 10.1530/rep-16-0517

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