Article
Clinical and virological predictors of sustained response with an interferon-based simeprevir regimen for patients with chronic genotype 1 hepatitis C virus infection.
The new microbiologica - 1 Jan 2017
D'Offizi Gianpiero, Cammà Calogero, Taibi Chiara, Schlag Michael, Weber Karin, Palma Maria, DeMasi Ralph, Janssen Katrien, Witek James, Lionetti Raffaella
Abstract excerpt
Simeprevir plus peg-interferon/ribavirin (PR) is approved to treat chronic hepatitis C (HCV) genotype 1 (GT1) and GT4 infection. This study aimed to assess baseline and on-treatment the factors predictive of sustained virologic response 12-weeks post-treatment (SVR12) in patients receiving 12 weeks of simeprevir plus PR followed by 12 or 36 weeks of PR. Data from participants in four studies (QUEST-1, QUEST-2,...
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