Article
Polyclonal emergence of vanA vancomycin-resistant Enterococcus faecium in Australia.
The Journal of antimicrobial chemotherapy - 1 Apr 2017
van Hal Sebastiaan J, Espedido Björn A, Coombs Geoffrey W, Howden Benjamin P, Korman Tony M, Nimmo Graeme R, Gosbell Iain B, Jensen Slade O
Abstract excerpt
Objectives: To investigate the genetic context associated with the emergence of vanA VRE in Australia. Methods: The whole genomes of 18 randomly selected vanA -positive Enterococcus faecium patient isolates, collected between 2011 and 2013 from hospitals in four Australian capitals, were sequenced and analysed. Results: In silico typing and transposon/plasmid assembly revealed that the sequenced isolates...
Topics
- Australia
- Bacterial Proteins
- Carbon-Oxygen Ligases
- DNA Transposable Elements
- Enterococcus faecium
- Genetic Variation
- Genome, Bacterial
- Gram-Positive Bacterial Infections
- Hospitals
- Humans
- Molecular Typing
- Plasmids
- Sequence Analysis, DNA