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Article

Clinical Efficacy of Afatinib Treatment for a Patient with Leptomeningeal Carcinomatosis.

Chemotherapy - 1 Jan 2017

Kawaguchi Yo, Hanaoka Jun, Hayashi Hideki, Mizusaki Naoki, Iihara Hirotoshi, Itoh Yoshinori, Sugiyama Tadashi

Abstract excerpt

Leptomeningeal metastases occur in 1% of patients with non-small-cell lung cancer. There have been several reports on the treatment of leptomeningeal metastases with afatinib. Our patient was a 41-year-old woman who had never smoked and was diagnosed with stage IV adenocarcinoma of the lung with an epidermal growth factor receptor (EGFR) mutation. She was treated with afatinib for the recurrence of leptomeningeal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28030859
DOI: 10.1159/000454727

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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