Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical development of gene- and cell-based therapies: overview of the European landscape

1 Jan 2016

Abstract excerpt

In the last decade, many clinical trials with gene- and cell-based therapies were performed and increasing interest in the development was established by (national) authorities, academic developers, and commercial companies. However, until now only eight products have received marketing authorization (MA) approval. In this study, a comprehensive overview of the clinical development of gene- and cell-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to CAR-T cell therapy research
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27990447
DOI: 10.1038/mtm.2016.73

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical development of gene- and cell-based therapies: overview of the European landscapePMID 27990447Read ↗

Development of Cell and Gene Therapies for Clinical Use in the US and EU: Summary of Regulatory GuidelinesSemantic proximity Read ↗

Gene therapies development: slow progress and promising prospectSemantic proximity Read ↗

Considerations for manufacturing of cell and gene medicines for clinical developmentSemantic proximity Read ↗

A few ethical issues in translational research for gene and cell therapySemantic proximity Read ↗

Considerations for Cell and Gene Therapy Programs Entering the Clinical SpaceSemantic proximity Read ↗

BJCP-EMA commentaries on the guideline on quality, non-clinical and clinical aspects of medicinal products containing genetically modified cells.Semantic proximity Read ↗

Advances and Challenges in the Development of Gene Therapy Medicinal Products for Rare DiseasesSemantic proximity Read ↗

EMA commentary on the guideline on quality, nonclinical and clinical aspects of medicinal products containing genetically modified cellsSemantic proximity Read ↗

The Past, Present, and (Near) Future of Gene Therapy and Gene EditingSemantic proximity Read ↗

ISSCR’s Guidelines for Stem Cell Research and Clinical Translation: Supporting development of safe and efficacious stem cell-based interventionsSemantic proximity Read ↗

The European landscape for gene therapies in orphan diseases: 6-year experience with the EMA Committee for Orphan Medicinal ProductsSemantic proximity Read ↗

Gene therapy clinical trials worldwide to 2017: An updateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.