Article
Genetic screening in patients with Retinoblastoma in Israel.
Familial cancer - 1 Sept 2015
Sagi Michal, Frenkel Avishag, Eilat Avital, Weinberg Naomi, Frenkel Shahar, Pe'er Jacob, Abeliovich Dvorah, Lerer Israela
Abstract excerpt
Retinoblastoma (Rb) is a childhood tumor (~1 in 20,000 live births) developing in the retina due to mutations in the RB1 gene. Identification of the oncogenic mutations in the RB1 gene is important for the clinical management and for genetic counseling to families with a child or a parent affected with the tumor. Here we present our experience in detecting the pathogenic mutations in blood samples, from 150...
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