Article
Expression of an immunogenic LTB-based chimeric protein targeting Zaire ebolavirus epitopes from GP1 in plant cells.
Plant cell reports - 1 Feb 2017
Ríos-Huerta Regina, Monreal-Escalante Elizabeth, Govea-Alonso Dania O, Angulo Carlos, Rosales-Mendoza Sergio
Abstract excerpt
KEY MESSAGE: An antigenic protein targeting two epitopes from the Zaire ebolavirus GP1 protein was expressed in plant cells rendering an antigen capable of inducing humoral responses in mouse when administered subcutaneously or orally. The 2014 Ebola outbreak made clear that new treatments and prophylactic strategies to fight this disease are needed. Since vaccination is an intervention that could achieve the...
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