Article
Association between PTPN22/CTLA-4 Gene Polymorphism and Allergic Rhinitis with Asthma in Children.
Iranian journal of allergy, asthma, and immunology - 1 Oct 2016
Song Shang Hua, Wang Xiao Qiang, Shen Yang, Hong Su Ling, Ke Xia
Abstract excerpt
Allergic rhinitis (AR) is an IgE-mediated upper airway disease, and its impact on asthma has been widely recognized. Protein tyrosine phosphatase non-receptor 22 (PTPN22) gene and the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) gene polymorphisms have been reported to be associated with several immune-related diseases. Here we investigated the reffect of these two genes' polymorphisms on the risk of AR...
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