Article
Inferring the Number of Contributors to Complex DNA Mixtures Using Three Methods: Exploring the Limits of Low-Template DNA Interpretation.
Journal of forensic sciences - 1 Mar 2017
Alfonse Lauren E, Tejada Genesis, Swaminathan Harish, Lun Desmond S, Grgicak Catherine M
Abstract excerpt
In forensic DNA casework, the interpretation of an evidentiary profile may be dependent upon the assumption on the number of individuals from whom the evidence arose. Three methods of inferring the number of contributors-NOCIt, maximum likelihood estimator, and maximum allele count, were evaluated using 100 test samples consisting of one to five contributors and 0.5-0.016 ng template DNA amplified with...
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