Physical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.

doi:10.1186/s12881-016-0352-9

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Article

Physical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.

BMC medical genetics - 1 Dec 2016

Wang Shuo, Song Jieyun, Shang Xiaorui, Chawla Nitesh, Yang Yide, Meng Xiangrui, Wang Haijun, Ma Jun

Abstract excerpt

BACKGROUND: The patatin like phospholipase containing domain 3 gene (PNPLA3) rs738409 C > G polymorphism, one of the most important gene polymorphisms involved in hepatic steatosis, has been reported to interact with different nutrients and dietary patterns on Non-Alcoholic Fatty Liver Disease (NAFLD), but no studies have focused on its interaction with physical activity or sedentary behavior. Therefore, this...

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Identifiers

PMID: 27905898
DOI: 10.1186/s12881-016-0352-9
PMCID: PMC5134284

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Physical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.PMID 27905898Read ↗

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