Article
MiR-148a the epigenetic regulator of bone homeostasis is increased in plasma of osteoporotic postmenopausal women.
Wiener klinische Wochenschrift - 1 Dec 2016
Bedene Ajda, Mencej Bedrač Simona, Ješe Lea, Marc Janja, Vrtačnik Peter, Preželj Janez, Kocjan Tomaž, Kranjc Tilen, Ostanek Barbara
Abstract excerpt
BACKGROUND: Osteoporosis is a prevalent skeletal disorder characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue, resulting in bone fragility and low-trauma fractures. Imaging techniques are routinely used to detect low bone mass; however, they are unable to identify deterioration of bone quality. Recently, microRNAs have emerged as regulators of bone remodelling and...
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