The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men.

doi:10.1002/jcsm.12139

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Article

The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men.

Journal of cachexia, sarcopenia and muscle - 1 Apr 2017

St-Jean-Pelletier Félix, Pion Charlotte H, Leduc-Gaudet Jean-Philippe, Sgarioto Nicolas, Zovilé Igor, Barbat-Artigas Sébastien, Reynaud Olivier, Alkaterji Feras, Lemieux François C, Grenon Alexis, Gaudreau Pierrette, Hepple Russell T, Chevalier Stéphanie, Belanger Marc, Morais José A, Aubertin-Leheudre Mylène, Gouspillou Gilles

Abstract excerpt

BACKGROUND: The exact impact of ageing on skeletal muscle phenotype and mitochondrial and lipid content remains controversial, probably because physical activity, which greatly influences muscle physiology, is rarely accounted for. The present study was therefore designed to investigate the effects of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, and mitochondrial and intramyocellular...

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PMID: 27897402
DOI: 10.1002/jcsm.12139
PMCID: PMC5377417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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