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Evaluation of Isolation Methods for Circulating Tumor Cells (CTCs)

1 Jan 2016

Abstract excerpt

BACKGROUND: Detection of CTCs is a poor prognostic factor for many cancer types; however, their very low frequency represents an obstacle for their detection. The objective of the current study was to compare the performance of commonly used methods for CTCs isolation. METHODS: The evaluated methods using spiking experiments of MCF7, SKBR3 and MDA MB-231 breast cancer cell lines were (i) ficoll density gradient...

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PMID: 27889762
DOI: 10.1159/000452556

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