Article
Molecular Basis of Congenital Factor XIII Deficiency in Iran.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Mar 2018
Dorgalaleh Akbar, Assadollahi Vahideh, Tabibian Shadi, Shamsizadeh Morteza
Abstract excerpt
Factor XIII deficiency (FXIIID) is an extremely rare autosomal recessive disorder that has the highest incidence in Iran. The FXIIID is primarily due to mutations in the FXIII-A gene, most of which are unique. In the current study, we report all identified mutations among Iranian patients. Among 483 patients, 366 (75.8%) were molecularly analyzed; 11 different mutations were observed. Of 11, 8 (72.7%) are...
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