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Article

Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing.

PloS one - 1 Jan 2016

Xu Jin, Spitale Robert C, Guan Linna, Flynn Ryan A, Torre Eduardo A, Li Rui, Raber Inbar, Qu Kun, Kern Dale, Knaggs Helen E, Chang Howard Y, Chang Anne Lynn S

Abstract excerpt

While much is known about genes that promote aging, little is known about genes that protect against or prevent aging, particularly in human skin. The main objective of this study was to perform an unbiased, whole transcriptome search for genes that associate with intrinsic skin youthfulness. To accomplish this, healthy women (n = 122) of European descent, ages 18-89 years with Fitzpatrick skin type I/II were...

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Source

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Identifiers

PMID: 27829007
DOI: 10.1371/journal.pone.0165913
PMCID: PMC5102383

Genes

HAS2
PHLDA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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