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Article

Consequences of extracellular trap formation in sepsis

5 Nov 2016

Abstract excerpt

PURPOSE OF REVIEW: This review will focus on in-vivo findings derived from animal models of sepsis regarding the trapping role of neutrophil extracellular traps (NETs) which is difficult to assess ex vivo. The NETotic response of neutrophils at sites of sterile injury or autoimmune disease is destructive as no antimicrobial advantage to the host is realized and dampening NETosis is largely beneficial. In early...

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Identifiers

PMID: 27820735
DOI: 10.1097/moh.0000000000000303

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