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Article

Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer.

Gut - 1 Jun 2017

Bao Ying, Prescott Jennifer, Yuan Chen, Zhang Mingfeng, Kraft Peter, Babic Ana, Morales-Oyarvide Vicente, Qian Zhi Rong, Buring Julie E, Cochrane Barbara B, Gaziano J Michael, Giovannucci Edward L, Manson JoAnn E, Ng Kimmie, Ogino Shuji, Rohan Thomas E, Sesso Howard D, Stampfer Meir J, Fuchs Charles S, De Vivo Immaculata, Amundadottir Laufey T, Wolpin Brian M

Abstract excerpt

OBJECTIVE: Telomere shortening occurs as an early event in pancreatic tumorigenesis, and genetic variants at the telomerase reverse transcriptase (TERT) gene region have been associated with pancreatic cancer risk. However, it is unknown whether prediagnostic leucocyte telomere length is associated with subsequent risk of pancreatic cancer. DESIGN: We measured prediagnostic leucocyte telomere length in 386...

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Identifiers

PMID: 27797938
DOI: 10.1136/gutjnl-2016-312510
PMCID: PMC5442267

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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