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Case report: Durable response to afatinib in a patient with lung cancer harboring two uncommon mutations of EGFR and a KRAS mutation.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2016

Tanizaki Junko, Banno Eri, Togashi Yosuke, Hayashi Hidetoshi, Sakai Kazuko, Takeda Masayuki, Kaneda Hiroyasu, Nishio Kazuto, Nakagawa Kazuhiko

Abstract excerpt

Comprehensive genomic profiling for non-small cell lung cancer (NSCLC) is likely to identify more patients with rare genetic alterations including uncommon epidermal growth factor receptor gene (EGFR) mutations. It remains unclear how such patients should be treated, however. We here report a case of NSCLC positive for two uncommon mutations of EGFR and a KRAS mutation, including its treatment with the...

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PMID: 27794398
DOI: 10.1016/j.lungcan.2016.09.001

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EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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