Article
BcsZ inhibits biofilm phenotypes and promotes virulence by blocking cellulose production in Salmonella enterica serovar Typhimurium.
Microbial cell factories - 19 Oct 2016
Ahmad Irfan, Rouf Syed Fazle, Sun Lei, Cimdins Annika, Shafeeq Sulman, Le Guyon Soazig, Schottkowski Marco, Rhen Mikael, Römling Ute
Abstract excerpt
BACKGROUND: Cellulose, a 1,4 beta-glucan polysaccharide, is produced by a variety of organisms including bacteria. Although the production of cellulose has a high biological, ecological and economical impact, regulatory mechanisms of cellulose biosynthesis are mostly unknown. Family eight cellulases are regularly associated with cellulose biosynthesis operons in bacteria; however, their function is poorly...
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