Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted Sequencing and Immunological Analysis Reveal the Involvement of Primary Immunodeficiency Genes in Pediatric IBD: a Japanese Multicenter Study.

Journal of clinical immunology - 1 Jan 2017

Suzuki Tasuku, Sasahara Yoji, Kikuchi Atsuo, Kakuta Humihiko, Kashiwabara Toshihiko, Ishige Takashi, Nakayama Yoshiko, Tanaka Masanori, Hoshino Akihiro, Kanegane Hirokazu, Abukawa Daiki, Kure Shigeo

Abstract excerpt

PURPOSE: Pediatric inflammatory bowel disease (IBD) is a heterogeneous disorder caused by multiple factors. Although genetic and immunological analyses are required for a definitive diagnosis, no reports of a comprehensive genetic study of a Japanese population are available. METHODS: In total, 35 Japanese patients <16 years of age suffering from IBD, including 27 patients aged <6 years with very early-onset IBD,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity

Share to Immunologic Deficiency Syndromes

Share to Inflammatory Bowel Diseases

Share to Inheritance Patterns

Share to Interleukin-10

Share to X-Linked Inhibitor of Apoptosis Protein

Source

Identifiers

PMID: 27747465
DOI: 10.1007/s10875-016-0339-5

Genes

XIAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted Sequencing and Immunological Analysis Reveal the Involvement of Primary Immunodeficiency Genes in Pediatric IBD: a Japanese Multicenter Study.PMID 27747465Read ↗

Primary Immunodeficiencies Associated With Early-Onset Inflammatory Bowel Disease in Southeast and East Asia.Semantic proximity Read ↗

The Treatment of Inflammatory Bowel Disease in Patients with Selected Primary Immunodeficiencies.Semantic proximity Read ↗

Clinical and Mutation Description of the First Iranian Cohort of Infantile Inflammatory Bowel Disease: The Iranian Primary Immunodeficiency Registry (IPIDR).Semantic proximity Read ↗

Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.Semantic proximity Read ↗

Clinical Features and Genetic Analysis of Taiwanese Primary Immunodeficiency Patients with Prolonged Diarrhea and Monogenetic Inflammatory Bowel Disease.Semantic proximity Read ↗

How genetic testing can lead to targeted management of XIAP deficiency-related inflammatory bowel disease.Semantic proximity Read ↗

Eosinophilic colitis in a boy with a novel XIAP mutation: a case report.Semantic proximity Read ↗

Inflammatory Bowel Disease With Lethal Disease Course Caused by a Nonsense Mutation in BIRC4 Encoding X-Linked Inhibitor of Apoptosis Protein (XIAP).Semantic proximity Read ↗

Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn’s DiseaseSemantic proximity Read ↗

Comprehensive mutation screening for 10 genes in Chinese patients suffering very early onset inflammatory bowel disease.Semantic proximity Read ↗

Severe combined immunodeficiencies: Expanding the mutation spectrum in Turkey and identification of 12 novel variants.Semantic proximity Read ↗

Is Whole Exome Sequencing Clinically Practical in the Management of Pediatric Crohn's Disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.