Article
Individualized Prediction of Changes in 6-Minute Walk Distance for Patients with Duchenne Muscular Dystrophy.
PloS one - 1 Jan 2016
Goemans Nathalie, Vanden Hauwe Marleen, Signorovitch James, Swallow Elyse, Song Jinlin
Abstract excerpt
BACKGROUND: Deficits in ambulatory function progress at heterogeneous rates among individuals with Duchenne muscular dystrophy (DMD). The resulting inherent variability in ambulatory outcomes has complicated the design of drug efficacy trials and clouded the interpretation of trial results. We developed a prediction model for 1-year change in the six minute walk distance (6MWD) among DMD patients, and compared...
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