The Pathogenesis of Resection-Associated Intestinal Adaptation

Abstract excerpt

After massive small-bowel resection, the remnant bowel compensates by a process termed adaptation . Adaptation is characterized by villus elongation and crypt deepening, which increases the capacity for absorption and digestion per unit length. The mechanisms/mediators of this important response are multiple. The purpose of this review is to highlight the major basic contributions in elucidating a more...

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