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Article

Before and after - Nutritional transformation of dysmorphism in a case of Costello syndrome.

European journal of medical genetics - 1 Nov 2016

Chiu Annie T G, Zhu Lixing, Mok Gary T K, Leung Gordon K C, Chow C B, Chung Brian H Y

Abstract excerpt

Costello syndrome is a type of RASopathy mapped to HRAS gene in chromosome 11, characterized by prenatal overgrowth, postnatal failure to thrive, classic facial gestalt and multisystem involvement including cardiomyopathy and intellectual disability. We present a 7 months old child with severe failure to thrive whose "subtle" facial dysmorphism at the time eluded clinical recognition of the syndrome. It was only...

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Source

Identifiers

PMID: 27705751
DOI: 10.1016/j.ejmg.2016.10.001

Genes

HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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