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Novel population of small tumour-initiating stem cells in the ovaries of women with borderline ovarian cancer

5 Oct 2016

Abstract excerpt

Small stem cells with diameters of up to 5 μm previously isolated from adult human ovaries indicated pluripotency and germinal lineage, especially primordial germ cells, and developed into primitive oocyte-like cells in vitro. Here, we show that a comparable population of small stem cells can be found in the ovarian tissue of women with borderline ovarian cancer, which, in contrast to small stem cells in...

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PMID: 27703207
DOI: 10.1038/srep34730

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