Article
MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study.
Cancer epidemiology - 1 Dec 2016
Peckham-Gregory Erin C, Thapa Dharma R, Martinson Jeremy, Duggal Priya, Penugonda Sudhir, Bream Jay H, Chang Po-Yin, Dandekar Sugandha, Chang Shen-Chih, Detels Roger, Martínez-Maza Otoniel, Zhang Zuo-Feng, Hussain Shehnaz K
Abstract excerpt
BACKGROUND: MicroRNAs, small non-coding RNAs involved in gene regulation, are implicated in lymphomagenesis. We evaluated whether genetic variations in microRNA coding regions, binding sites, or biogenesis genes (collectively referred to as miRNA-SNPs) were associated with risk of AIDS-associated non-Hodgkin lymphoma (AIDS-NHL), and serum levels of four lymphoma-related microRNAs. METHODS: Twenty-five miRNA-SNPs...
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