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Article

Prognostic impact of pretreatment cytogenetics in adult P hiladelphia chromosome–negative acute lymphoblastic leukemia in the era of minimal residual disease

3 Oct 2016

Abstract excerpt

BACKGROUND: The introduction of novel prognostic factors such as minimal residual disease (MRD) and genomic profiling has led to the reevaluation of the role of cytogenetics and other conventional factors in risk stratification for acute lymphoblastic leukemia (ALL). METHODS: This study assessed the impact of baseline cytogenetics on the outcomes of 428 adult patients with Philadelphia chromosome-negative ALL who...

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PMID: 27696391
DOI: 10.1002/cncr.30376

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