Article
Identification of genetic variation in the lncRNA HOTAIR associated with HPV16-related cervical cancer pathogenesis.
Cellular oncology (Dordrecht, Netherlands) - 1 Dec 2016
Sharma Saha Sweta, Roy Chowdhury Rahul, Mondal Nidhu Ranjan, Chakravarty Biman, Chatterjee Tanmay, Roy Sudipta, Sengupta Sharmila
Abstract excerpt
PURPOSE: Previously, over-expression of the long noncoding RNA (lncRNA) HOTAIR has been found to be associated with the invasive and metastatic capacities of several epithelial cancers, including cervical cancer (CaCx). Here, we aimed at identifying functionally relevant genetic variants that may be employed to differentiate between clinically distinct CaCx subtypes, i.e., those exhibiting high HOTAIR levels and...
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