Article
Telmisartan increases vascular reparative capacity in older HIV-infected adults: a pilot study.
HIV clinical trials - 1 Nov 2016
Lake Jordan E, Seang Sophie, Kelesidis Theodoros, Currier Judith S, Yang Otto O
Abstract excerpt
BACKGROUND: Endothelial progenitor cells (EPCs) are bone marrow-derived cells that contribute to vascular repair. EPCs may be reduced in HIV-infected (HIV+) persons, contributing to cardiovascular disease (CVD). Telmisartan is an angiotensin receptor blocker that increases EPCs in HIV-uninfected adults. OBJECTIVE: To assess telmisartan's effects on EPC number and immunophenotype in older HIV + adults at risk for...
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