Article
Regulatory SNPs Alter the Gene Expression of Diabetic Retinopathy Associated Secretary Factors.
International journal of medical sciences - 1 Jan 2016
Chen Chian-Feng, Liou Shiow-Wen, Wu Hsin-Han, Lin Chin-Hui, Huang Li-Shan, Woung Lin-Chung, Tsai Ching-Yao
Abstract excerpt
OBJECTIVES: Diabetic retinopathy (DR) is a common microvascular complication in both type I and type II diabetes. Several previous reports indicated the serum centration of some secretary factors were highly associated with DR. Therefore, we hypothesis regulatory SNPs (rSNPs) genotype in secretary factors may alter these gene expression and lead to DR. METHODS: At first, pyrosequencing were applying to screen the...
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