Article
Functional analysis of molecular interactions in synthetic auxin response circuits.
Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2016
Pierre-Jerome Edith, Moss Britney L, Lanctot Amy, Hageman Amber, Nemhauser Jennifer L
Abstract excerpt
Auxin-regulated transcription pivots on the interaction between the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) repressor proteins and the AUXIN RESPONSE FACTOR (ARF) transcription factors. Recent structural analyses of ARFs and Aux/IAAs have raised questions about the functional complexes driving auxin transcriptional responses. To parse the nature and significance of ARF-DNA and ARF-Aux/IAA interactions, we analyzed...
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