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Rethinking the importance of paroxysmal and unusual symptoms as first clinical manifestation of multiple sclerosis: They do matter.

Multiple sclerosis and related disorders - 1 Sept 2016

Ehling Rainer, Bsteh Gabriel, Di Pauli Franziska, Hegen Harald, Auer Michael, Obermair Karin, Wagner Michaela, Deisenhammer Florian, Reindl Markus, Berger Thomas

Abstract excerpt

BACKGROUND: Paroxysmal (PS) and unusual symptoms (US) as initial manifestation of multiple sclerosis (MS) are rare and often thought to indicate "benign" MS. OBJECTIVE: To investigate prevalence and clinical disease course of patients experiencing PS or US as first clinical manifestation. METHODS: Clinical, MRI and cerebrospinal fluid data of patients presenting with PS and US were obtained retrospectively and...

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PMID: 27645364
DOI: 10.1016/j.msard.2016.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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