Article
Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus.
Oncotarget - 18 Oct 2016
Shi Aiwu, Wen Juan, Liu Guangquan, Liu Heng, Fu Ziyi, Zhou Jing, Zhu Yao, Liu Yaoqiu, Guo Xirong, Xu Jianguo
Abstract excerpt
Vitamin D (VD) deficiency during pregnancy has been repeatedly linked to an increased gestational diabetes mellitus (GDM) risk. We sought to determine the influences of genetic variants in vitamin D signaling pathways on the risk of GDM. In this study, we genotyped 15 single nucleotide polymorphisms (SNPs) within 8 representative genes (CYP27A1, CYP27B1, CYP24A1, VDR, RXRA, RXRB, RXRG and GC) of the vitamin D...
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