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SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication

14 Sept 2016

Abstract excerpt

Accumulating evidence suggests that viruses hijack cellular proteins to circumvent the host immune system. Ubiquitination and SUMOylation are extensively studied posttranslational modifications (PTMs) that play critical roles in diverse biological processes. Cross talk between ubiquitination and SUMOylation of both host and viral proteins has been reported to result in distinct functional consequences....

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PMID: 27630238
DOI: 10.1128/jvi.01756-16

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