Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication

29 Aug 2016

Abstract excerpt

Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of these unconventional functions of ATG proteins. We determined the effects of the depletion of each ATG proteome component on the replication of six...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Mosquito-borne diseases and control
Share to Plant Virus Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27573464
DOI: 10.1083/jcb.201602046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replicationPMID 27573464Read ↗

Autophagy and RNA virus interactomes reveal IRGM as a common targetSemantic proximity Read ↗

TRIM proteins: New players in virus-induced autophagySemantic proximity Read ↗

Viruses and the autophagy machinerySemantic proximity Read ↗

The role of autophagy in viral infectionsSemantic proximity Read ↗

Autophagy and Viruses: Adversaries or Allies?Semantic proximity Read ↗

Interplay between the cellular autophagy machinery and positive-stranded RNA virusesSemantic proximity Read ↗

Autophagy in Negative-Strand RNA Virus InfectionSemantic proximity Read ↗

Clearance or Hijack: Universal Interplay Mechanisms Between Viruses and Host Autophagy From Plants to AnimalsSemantic proximity Read ↗

Autophagy in Virus Infection: A Race between Host Immune Response and Viral AntagonismSemantic proximity Read ↗

The Multifaceted Roles of Autophagy in Flavivirus-Host InteractionsSemantic proximity Read ↗

Differential and convergent utilization of autophagy components by positive-strand RNA virusesSemantic proximity Read ↗

Autophagy in Viral Replication and PathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.