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Article

HOGA1 Gene Mutations of Primary Hyperoxaluria Type 3 in Tunisian Patients.

Journal of clinical laboratory analysis - 1 May 2017

M'dimegh Saoussen, Aquaviva-Bourdain Cécile, Omezzine Asma, Souche Geneviéve, M'barek Ibtihel, Abidi Kamel, Gargah Tahar, Abroug Saoussen, Bouslama Ali

Abstract excerpt

BACKGROUND: Primary hyperoxaluria type 3 (PH3) is due to mutations in the recently identified 4-hydroxy-2-oxoglutarate aldolase (HOGA1) gene. PH3 might be the least severe form with a milder phenotype with good preservation of kidney function in most patients. The aim of this study was to report three PH3 cases carrying mutations in HOGA1. MATERIALS AND METHODS: Genetic analysis of HOGA1 was performed in patients...

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Source

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Identifiers

PMID: 27561601
DOI: 10.1002/jcla.22053
PMCID: PMC6817302

Genes

HOGA1
AGXT
GRHPR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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