Article
Evidence for Within-Host Genetic Recombination among the Human Pegiviral Strains in HIV Infected Subjects.
PloS one - 1 Jan 2016
Wu Haoming, Padhi Abinash, Xu Junqiang, Gong Xiaoyan, Tien Po
Abstract excerpt
The non-pathogenic Human Pegivirus (HPgV, formerly GBV-C/HGV), the most prevalent RNA virus worldwide, is known to be associated with reduced morbidity and mortality in HIV-infected individuals. Although previous studies documented its ubiquity and important role in HIV-infected individuals, little is known about the underlying genetic mechanisms that maintain high genetic diversity of HPgV within the...
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