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Article

Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue-derived endocrine factor with a potential role in fetal growth.

Translational research : the journal of laboratory and clinical medicine - 1 Dec 2016

Martinez-Perez Bruno, Ejarque Miriam, Gutierrez Cristina, Nuñez-Roa Catalina, Roche Kelly, Vila-Bedmar Rocio, Ballesteros Mónica, Redondo-Angulo Ibon, Planavila Anna, Villarroya Francesc, Vendrell Joan, Fernández-Veledo Sonia, Megía Ana

Abstract excerpt

Angiopoietin-like protein 8 (ANGPTL8), a protein implicated in lipid and glucose homeostasis, is present only in mammals, suggesting that it is involved in processes unique to these vertebrates such as pregnancy and homeothermy. We explored the role of ANGPTL8 in maternal-fetal crosstalk and its relationship with newborn adiposity. In a longitudinal analysis of healthy pregnant women, ANGPTL8 levels decreased...

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Source

Identifiers

PMID: 27469268
DOI: 10.1016/j.trsl.2016.06.012

Genes

ANGPTL8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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