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Follicular growth after xenotransplantation of cryopreserved/thawed human ovarian tissue in SCID mice: dynamics and molecular aspects

27 Jul 2016

Abstract excerpt

To study the influence of xenotransplantation on follicular recruitment and growth in cryopreserved/thawed human ovarian tissue. Two 3-mm pieces of cryopreserved/thawed human ovarian tissue obtained from female cancer patients ( n = 11) were xenotransplanted into a subcutaneous neck pouch of 6-week-old ovarectomized SCID mice ( n = 33) for 4 ( n = 18) and 12 ( n = 15) weeks. Thirty-two out of 33 mice survived the...

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PMID: 27465301
DOI: 10.1007/s10815-016-0769-2

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