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Article

Characterization of VP1 sequence of Coxsackievirus A16 isolates by Bayesian evolutionary method.

Virology journal - 28 Jul 2016

Zhao Guolian, Zhang Xun, Wang Changmin, Wang Guoqing, Li Fan

Abstract excerpt

BACKGROUND: Coxsackievirus A16 (CV-A16), a major etiopathologic cause of pediatric hand, foot, and mouth disease (HFMD) worldwide, has been reported to have caused several fatalities. Revealing the evolutionary and epidemiologic dynamics of CV-A16 across time and space is central to understanding its outbreak potential. METHODS: In this study, we isolated six CV-A16 strains in China's Jilin province and construct...

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PMID: 27464503
DOI: 10.1186/s12985-016-0578-3
PMCID: PMC4963925

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