Article
Frequent BRAF or EGFR Mutations in Ciliated Muconodular Papillary Tumors of the Lung.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2016
Kamata Tsugumasa, Sunami Kuniko, Yoshida Akihiko, Shiraishi Kouya, Furuta Koh, Shimada Yoko, Katai Hitoshi, Watanabe Shun-Ichi, Asamura Hisao, Kohno Takashi, Tsuta Koji
Abstract excerpt
INTRODUCTION: Ciliated muconodular papillary tumors (CMPTs) are recently characterized, rare peripheral nodules of the lung. These small tumors are histologically comprised of a vaguely organized mixture of nonatypical ciliated columnar cells, mucous cells, and basal cells, and consistently follow a benign clinical course. However, the histogenesis of CMPTs remains uncertain. METHODS: We performed detailed...
Topics
- Aged
- Carcinoma, Papillary
- ErbB Receptors
- Female
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins B-raf