Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The GlnR Regulon in Streptococcus mutans Is Differentially Regulated by GlnR and PmrA.

PloS one - 1 Jan 2016

Chen Yi-Ywan M, Chen Yueh-Ying, Hung Jui-Lung, Chen Pei-Min, Chia Jean-San

Abstract excerpt

GlnR-mediated repression of the GlnR regulon at acidic pH is required for optimal acid tolerance in Streptococcus mutans, the etiologic agent for dental caries. Unlike most streptococci, the GlnR regulon is also regulated by newly identified PmrA (SMUGS5_RS05810) at the transcriptional level in S. mutans GS5. Results from gel mobility shift assays confirmed that both GlnR and PmrA recognized the putative GlnR box...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Carbohydrates
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Models, Biological

Share to Regulon

Share to Streptococcus mutans

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 27454482
DOI: 10.1371/journal.pone.0159599
PMCID: PMC4959772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The GlnR Regulon in Streptococcus mutans Is Differentially Regulated by GlnR and PmrA.PMID 27454482Read ↗

Effects of Arginine on Streptococcus mutans Growth, Virulence Gene Expression, and Stress ToleranceSemantic proximity Read ↗

Regulation of Glutamine and Glutamate Metabolism by GlnR and GlnA in Streptococcus pneumoniaeSemantic proximity Read ↗

GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence.Semantic proximity Read ↗

A GntR Family Transcription Factor in Streptococcus mutans Regulates Biofilm Formation and Expression of Multiple Sugar Transporter GenesSemantic proximity Read ↗

Identification and functional analysis of an ammonium transporter in Streptococcus mutans.Semantic proximity Read ↗

Effects of RelA on key virulence properties of planktonic and biofilm populations of Streptococcus mutans.Semantic proximity Read ↗

Site-Specific Contributions of Glutamine-Dependent Regulator GlnR and GlnR-Regulated Genes to Virulence of <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge InteractionsSemantic proximity Read ↗

Characterization of mleR, a positive regulator of malolactic fermentation and part of the acid tolerance response in Streptococcus mutansSemantic proximity Read ↗

RgpF Is Required for Maintenance of Stress Tolerance and Virulence in Streptococcus mutans.Semantic proximity Read ↗

Identification of DNA sequences involved in regulating Bacillus subtilis glnRA expression by the nitrogen source.Semantic proximity Read ↗

Effects of dual deletion of glnR and mtrA on expression of nitrogen metabolism genes in Streptomyces venezuelaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.