Article
Orderly Replication and Segregation of the Four Replicons of Burkholderia cenocepacia J2315.
PLoS genetics - 1 Jul 2016
Du Wen-Li, Dubarry Nelly, Passot Fanny M, Kamgoué Alain, Murray Heath, Lane David, Pasta Franck
Abstract excerpt
Bacterial genomes typically consist of a single chromosome and, optionally, one or more plasmids. But whole-genome sequencing reveals about ten per-cent of them to be multipartite, with additional replicons which by size and indispensability are considered secondary chromosomes. This raises the questions of how their replication and partition is managed without compromising genome stability and of how such...
Topics
- Bacterial Proteins
- Burkholderia cenocepacia
- Cell Cycle
- Chromosome Segregation
- Chromosomes
- Chromosomes, Bacterial
- DNA Replication
- Escherichia coli
- Gene Deletion
- Genes, Bacterial
- Genome, Bacterial
- Microscopy, Fluorescence
- Mutation
- Plasmids