Cerebral cavernous malformations with diffuse manifestation: A benign entity?

doi:10.1016/j.jns.2016.06.012

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Article

Cerebral cavernous malformations with diffuse manifestation: A benign entity?

Journal of the neurological sciences - 15 Aug 2016

Tsutsumi Satoshi, Ogino Ikuko, Miyajima Masakazu, Arai Hajime, Ito Masanori, Yasumoto Yukimasa

Abstract excerpt

PURPOSE: Cerebral cavernous malformations (CCMs) are a distinct cerebrovascular disease. A fraction of CCMs present as diffuse manifestations distributed over the cerebral hemispheres, cerebellum, and brainstem. The purpose of the present study was to explore the clinical picture of such CCMs. ME...

Topics

Adult
Aged
Apoptosis Regulatory Proteins
Brain
Carrier Proteins
Disease Progression
Female
Follow-Up Studies
Hemangioma, Cavernous, Central Nervous System
Humans
KRIT1 Protein
Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Membrane Proteins

Microtubule-Associated Proteins

Middle Aged

Mutation

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 27423615
DOI: 10.1016/j.jns.2016.06.012

Genes

CCM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27423615-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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