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Article

Genomic causes of multiple cerebral cavernous malformations in a Japanese population.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 May 2013

Tsutsumi Satoshi, Ogino Ikuko, Miyajima Masakazu, Ikeda Tomomi, Shindo Noriko, Yasumoto Yukimasa, Ito Masanori, Arai Hajime

Abstract excerpt

Cerebral cavernous malformation (CCM) is a hamartomatous vascular disease affecting the central nervous system. A fraction of CCM are thought to arise in association with genomic mutations in the cerebral cavernous malformation 1 (CCM1) (KRIT1), CCM2 (MGC4607), and CCM3 (PDCD10) genes. In the present study, 18 Japanese patients with multiple CCM (10 with familial type and eight with sporadic type), underwent...

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Identifiers

PMID: 23485406
DOI: 10.1016/j.jocn.2012.05.041

Genes

CCM2
PDCD10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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