Article
HANDS2: accurate assignment of homoeallelic base-identity in allopolyploids despite missing data.
Scientific reports - 5 Jul 2016
Khan Amina, Belfield Eric J, Harberd Nicholas P, Mithani Aziz
Abstract excerpt
Characterization of homoeallelic base-identity in allopolyploids is difficult since homeologous subgenomes are closely related and becomes further challenging if diploid-progenitor data is missing. We present HANDS2, a next-generation sequencing-based tool that enables highly accurate (>90%) genome-wide discovery of homeolog-specific base-identity in allopolyploids even in the absence of a diploid-progenitor. We...
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