Article
Gene signatures of estrogen and progesterone receptor pathways predict the prognosis of colorectal cancer
4 Jul 2016
Abstract excerpt
The associations of estrogen receptor (ER) and progesterone receptor (PR) pathways with the prognosis of colorectal cancer (CRC) are still controversial. The aim of this study was to readdress these issues by introducing a gene signature-based approach to semiquantitate pathway activity. In this approach, the ER and PR pathway activities in CRC were computed based on the expression profiles of the signature genes...
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