Article
Burkholderia pseudomallei rpoS mediates iNOS suppression in human hepatocyte (HC04) cells.
FEMS microbiology letters - 1 Aug 2016
Sanongkiet Sucharat, Ponnikorn Saranyoo, Udomsangpetch Rachanee, Tungpradabkul Sumalee
Abstract excerpt
Burkholderia pseudomallei is an intracellular Gram-negative bacterial pathogen and the causative agent of melioidosis, a widespread disease in Southeast Asia. Reactive nitrogen, in an intermediate form of nitric oxide (NO), is one of the first lines of defense used by host cells to eliminate intracellular pathogens, through the stimulation of inducible nitric oxide synthase (iNOS). Studies in phagocytotic cells...
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